美国冷泉港实验室离子通道生理学和受体生物化学博士后职位

Postdoctoral position in ion channel physiology and receptor biochemistry
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The laboratory of Hiro Furukawa at Cold Spring Harbor Laboratory (CSHL) is seeking an enthusiastic postdoc with dynamic interests in solving problems in neurological diseases and cancer using biochemical and biophysical techniques. We are especially looking for a scientist with specialty in electrophysiology including patch-clamp recording, single channel recording, and slice recording. We aim to understand the molecular assembly and function of neuronal synapses. We conduct protein purification from brain preparations, protein identification, tissue culture-based validation, electrophysiology, and structural biology (x-ray crystallography and electron microscopy) to achieve the above goal. We also conduct structure-function studies by electrophysiology to understand pharmacological properties of ion channels with a scope to develop therapeutic compounds for neurological diseases and cancer. We have a state-of-the-art equipment and facility to conduct structural biology, electrophysiology, proteomics, imaging, and biochemistry. CSHL offers a unique scientific environment to interact with scientists within the institute as well as from outside at the prestigious CSHL courses and meetings (including courses such as Ion channel and synaptic transmission and Advanced techniques in molecular neuroscience). Highly interactive and educative nature of CSHL has traditionally created many successful independent scientists with unique and innovative visions. A qualified candidate should hold or soon expected to hold (within ~1yr) Ph.D. in the area of electrophysiology or molecular neuroscience. Please see the lab website (http://www.cshl.edu/public/SCIENCE/furukawa.html – will be updated soon) for further information and send CV with a brief research statement as well as 2-3 contacts for references to furukawa@cshl.edu.